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ViewAttendees 5

GP3a - The Burden of Head and Neck Cancer in the United States: 1990-2017

Thursday, September 30, 2021
8:50 AM - 8:57 AM CDT
Location: Davidson Ballroom, Music City Center
Live-streamed
Estimated Incidence of Head and Neck Cancer in the United States, 2017

Change in Incidence of Head and Neck Cancer in the United States, 1990 - 2017

    Oral Abstract Presenter(s)

  • David C. Ludwig, DDS, MD

    Resident
    University of Washington Department of Oral and Maxillofacial Surgery
    Seattle, Washington

    Nothing to disclose.

    • Co-Author(s)

  • SM

    Shane D. Morrison, MD

    Fellow
    University of Michigan, Division of Plastic Surgery
    Seattle, Washington

    Nothing to disclose.

  • Jasjit K. Dillon, DDS, MBBS, FACS

    Professor & Chief, Program Director
    University of Washington
    Seattle, Washington

    Nothing to disclose.

Abstract:

Introduction: Head and neck cancers (HNC) are among the most common malignancies in the United States and are a significant cause of morbidity and mortality. Traditional risk factors for HNC include tobacco, alcohol, and Human Papillomavirus (HPV) infection. Geographic location has also been shown to play a role, whether directly or indirectly.1,2 The purpose of this study was to describe the incidence, mortality, and geographic variability of HNC within the United States between 1990 and 2017.

Methods: The Global Burden of Diseases Study 2017, which models incidence and mortality, was used to obtain incidence and mortality data for “lip and oral cavity cancer," “nasopharynx cancer," “other pharynx cancer” (tonsil, oropharynx, and hypopharynx), and “larynx cancer” for the United States between 1990 and 2017.

Results: The overall incidence rate of HNC increased (annual percent change [APC] = 0.23, 95% CI: 0.1-0.3) from 1990 through 2017 while overall mortality decreased (APC = -0.37, 95% CI: -0.4 to -0.3). The anatomic sub-site that saw the largest increase in incidence was “other pharynx” (APC = 1.07, 95% CI: 0.9-1.2). In 2017, those in the West had the lowest incidence while those in the South had the highest (15.7 and 20.8 per 100000 individuals, respectively).

Discussion: The incidence of HNC in the United States increased between 1990 and 2017. This was driven by larger increases in those sites more prone to HPV-related HNC. While there exists geographic variability in the burden of this disease, additional studies are needed to further understand the impact of patient-specific factors.

References: 1. Mourad M, Jetmore T, Jategaonkar AA, et al: Epidemiological trends of head and neck cancer in the United States: a SEER population study. J Oral Maxillofac Surg 75:12:2562-2572, 2017
2. Choi SH, Terrell JE, Fowler KE, et al: Socioeconomic and other demographic disparities predicting survival among head and neck cancer patients. PLoS ONE 11:3:e0149886, 2016